Depsides and depsidones
Medchemexpress LLC Sor-C13 Tfa | 99.3% | 1565.81 (free acid) | 10 MG
SOR-C13 TFA is a carboxy-terminal truncated peptide that acts as a high-affinity TRPV6 antagonist with an IC50 value of 14 nM. It has shown anticancer activity and targets TRPV6, a non-voltage gated calcium channel associated with malignancy and poor prognosis in breast cancer.
- High-affinity TRPV6 antagonist
- Exhibits anticancer activity
- Targets non-voltage gated calcium channel TRPV6
- Potentially useful in breast cancer research
Apexbio Technology LLC Alogliptin Benzoate 850649-62-6 10mg
Alogliptin Benzoate (CAS 850649-62-6) is a potent and highly selective inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC50 below 10 nM By suppressing DPP-4 activity alogliptin elevates active GLP-1 levels leading to improved glycemic parameters In ob/ob mouse models chronic administration results in dose-dependent reductions in plasma DPP-4 activity non-fasting blood glucose glycated hemoglobin and triglycerides along with increased insulin secretion and pancreatic insulin content Alogliptin Benzoate is widely used in research focused on incretin biology glucose homeostasis and the pharmacological modulation of DPP-4
Medchemexpress LLC Alogliptin Benzoate (SYR 322) | 850649-62-6 | 100.0% | C25H27N5O4 | 200 MG
Alogliptin Benzoate (SYR-322) is a potent, selective, and orally active inhibitor of DPP-4 with an IC50 of <10 nM, exhibiting over 10,000-fold selectivity over DPP-8 and DPP-9. It is suitable for research into type 2 diabetes.
- Potent, selective, and orally active inhibitor of DPP-4.
- Inhibits LPS-induced extracellular signal-regulated kinase (ERK) phosphorylation in U937 cells.
- Inhibits LPS-stimulated MMP-1 secretion and mRNA expression mediated by the ERK pathway in U937 cells.
- Improves glucose tolerance and increases plasma insulin levels in female Wistar fatty rats.
- Reduces infarction area and improves brain vascular integrity in middle cerebral artery occlusion (MCAO) mice.
Cayman Chemical EUK 118 Neurochemicals
A synthetic catalytic scavenger of reactive oxygen species, with reduced activity compared to EUK 8 and EUK 134
Apexbio Technology LLC Denatonium benzoate 3734-33-6 200mg
Denatonium benzoate is a small-molecule agonist targeting bitter taste receptors (TAS2Rs) It is designed to activate TAS2Rs thereby initiating intracellular signaling cascades involved in metabolic regulation and immune response Denatonium benzoate exerts its biological activity primarily through binding and activating TAS2Rs expressed on multiple cell populations In laboratory studies Denatonium benzoate demonstrates receptor activation contributing to investigations of taste receptor activation and insulin secretion Based on these pharmacological properties Denatonium benzoate holds research potential in elucidating glucose homeostasis metabolic functions immune cell activation and the role of bitter taste signaling in immunity and allergic responses
Medchemexpress LLC Alogliptin (Benzoate) | 850649-62-6 | 99.7% | C25H27N5O4 | 25 MG
Alogliptin (Benzoate) is the analytical standard of Alogliptin (Benzoate), intended for research and analytical applications. It is a potent, selective, and orally active inhibitor of DPP-4 with an IC50 of <10 nM, exhibiting high selectivity over DPP-8 and DPP-9. This compound can be used for the research of type 2 diabetes and is suitable for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Used for research and analytical applications
- Potent, selective, and orally active inhibitor of DPP-4
- Exhibits high selectivity over DPP-8 and DPP-9
- Suitable for type 2 diabetes research
- Ideal for HPLC, GC, and MS research experiments
Medchemexpress LLC Benzyl Benzoate | 120-51-4 | 99.98% | 5 G
Benzyl benzoate, also known as Phenylmethyl benzoate, is an orally active anti-scabies agent, acaricide, and fungicide. It also acts as an angiotensin II inhibitor, providing antihypertensive effects. This compound is versatile, finding applications in perfumes, pharmaceuticals, and the food industry.
- Orally active anti-scabies agent
- Effective acaricide and fungicide
- Angiotensin II inhibitor with antihypertensive effects
- Suitable for use in perfumes, pharmaceuticals, and food industry